臺大生技所

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 游舒涵
專任
職稱 助理教授
姓名 游舒涵
聯絡電話 886-2-3366-6007
Fax 02-3366-6001
電子郵件 shuhanyu@ntu.edu.tw
個人網址 https://shuhanyu.wixsite.com/website
經歷 國立臺灣大學 生物科技研究所 助理教授 2020月01日迄今

國防醫學院 生命科學研究所 專案助理教授 2018年 ~ 2020年
學歷 美國 約翰霍普金斯大學 病理學研究所 博士 2010.07 ~ 2015.03 
授課領域 免疫學技術抗體工具
幹細胞生物學
專題討論
專題研究
研究專長 生物腫瘤微環境
細胞輸入療法
個人化醫療
自傳
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游舒涵助理教授實驗室 (The S.H.Y. Lab) 研究主軸,包含腫瘤免疫微環境研究 Tumor Immune Microenvironment (TIME)、個人化醫療 (Personalize Medicine)、細胞輸入療法 (Adoptive Cell Therapy, ACT)。腫瘤免疫微環境 (TIME) 包含腫瘤細胞,腫瘤浸潤性免疫細胞,癌症相關纖維母細胞,腫瘤血管系統和細胞外基質,這些會共同促進腫瘤免受宿主免疫系統攻擊,進而支持腫瘤生長和轉移。針對病人腫瘤組織進行分析,研究其腫瘤及周邊組織免疫細胞的組成,將可建立一套「標準化分析」,並運用於精緻化醫療及個人化醫療。

游博士實驗室所建立之腫瘤微環境研究平台,可運用在犬貓腫瘤及疾病治療機轉之探討。亦可整合愛因斯坦計畫中初步在非小細胞肺癌研究成果,配合游博士在微生物學、免疫學以及腫瘤微環境等專長,帶入非小細胞肺癌精準醫療領域中。研究成果將可幫助臨床醫師針對不同病人的腫瘤免疫微環境進行個人化醫療診斷,大幅下修藥物需求與治療花費,同時也能避免高劑量、長期且持續性給予藥物所帶來的副作用。
 
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WE ARE RECRUITING!!
 
誠徵熱血新人中!!
年度 論文名稱
2019 Korangath P, Barnett J, Sharma A, Henderson E, Stewart J, Yu SH, Kandala SK, Yang CT, Caserto JS, Hedayati M, Armstrong TD, Jaffee E, Gruettner C, Zhou XC, Fu W, Hu C, Sukumar S, Simons BW, and Ivkov R., Nanoparticle interactions with immune cells dominate tumor retention and induce T cell-mediated tumor suppression in models of breast cancer(In press), Science Advances, (SCI)
2019 Yu SH, Maynard JP, Vaghasia AM, De Marzo AM, Drake CG, Sfanos KS, A role for paracrine interleukin-6 signaling in the tumor microenvironment in prostate tumor growth, Prostate, 79, pp215-222, (SCI)
2018 Shrestha E, White JR, Yu SH, Kulac I, Ertunc O, De Marzo AM, Yegnasubramanian S, Mangold LA, Partin AW, Sfanos KS, Profiling the urinary microbiome in men with positive versus negative biopsies for prostate cancer, J Urol, 199, pp161-171, (SCI)
2015 Sfanos KS, Canene-Adams K, Hempel H, Yu SH, Simons B, Schaeffer A, Schaeffer E, Nelson G, De Marzo AM, Bacterial Prostatitis Enhances 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine (PhIP)-Induced Cancer at Multiple Sites., Cancer Prev Res (Phila), 8, pp683-692, (SCI)
2014 Le A, Stine ZE, Nguyen C, Afzal J, Sun P, Hamaker M, Siegel NM, Gouw A, Kang BK, Yu SH, Cochran RL, Sailor KA, Song H, Dang CV, Tumorigenicity of hypoxic respiring cancer cells revealed by a hypoxia-cell cycle dual reporter, Proc Natl Acad Sci U S A, 111, pp12486-12491, (SCI)
2013 Shinohara DB, Vaghasia AM, Yu SH, Mak TN, Brüggemann H, Nelson WG, De Marzo AM, Yegnasubramanian S, Sfanos KS, A mouse model of chronic prostatic inflammation using a human prostate cancer-derived isolate of Propionibacterium acnes, Prostate, 73, pp1007-1015, (SCI)
2012 Mak TN*, Yu SH*, De Marzo AM, Brüggemann H, Sfanos KS, Multilocus sequence typing (MLST) analysis of Propionibacterium acnes isolates from radical prostatectomy specimens, Prostate, 73, pp770-777
類別 年度 獎項名稱 頒獎單位
校外榮譽 2018 愛因斯坦培植計畫 科技部
校外榮譽 2013 Excellence in Translational Research, Young Investigator Award
校外榮譽 2012 Singapore-Global Young Scientist Summit, Singapore Government Travel Award
校外榮譽 2012 Government Scholarship (公費留考) Ministry of Education
校外榮譽 2010 Young Scientist Award 17th East Asia Joint Conference on Biomedical Research
校外榮譽 2006 Undergraduate Research Fellowship Republic of China National Science Council
 



計畫主持人 游舒涵

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葉致宏 (博一)

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彭冠儒 (碩一)

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胡隨芸 (碩一)
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尤韋傑 (大四)

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陳威廷 (Previous Member)

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林瑋晨 (研究助理)

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