臺大生技所

:::
 劉嚞睿
專任
職稱 教授
姓名 劉嚞睿
聯絡電話 886-2-3366-6011
電子郵件 jrliu@ntu.edu.tw
經歷 臺大生技所教授:2013/8~
臺大動科系教授:2013/8~
中研院農生中心研究員:2017/8~
臺大生技所所長:2014/8-2020/7
行政院科技會報辦公室科技政策諮詢專家室領域專家
行政院衛生福利部健康食品審議委員會審議委員
行政院農業委員會基因改造飼料或飼料添加物查驗登記審議委員會審議委員
 
研究專長 基因工程
​蛋白質工程
機能性食品研究
益生菌研究
新穎性飼料添加物開發
年度 論文名稱
2020 Sy, J. B. A., T. C. Hsu, A. Limaye, and J. R. Liu*, Oral administration with a traditional fermented multi-fruit beverage modulates non-specific and antigen-specific immune responses in BALB/c mice, PLoS One, 15, ppe0233047-, (SCI)
2020 Chang-Liao, W. P., A. Lee, Y. H. Chiu, H. W. Chang, and J. R. Liu*, Isolation of a Leuconostoc mesenteroides strain with anti-porcine epidemic diarrhea virus activities from kefir grains, Frontiers in Microbiology, 11, pp1578-, (SCI)
2020 Cheng, Y. C. and J. R. Liu*, Effect of Lactobacillus rhamnosus GG on energy metabolism, leptin resistance, and gut microbiota in mice with diet-induced obesity, Nutrients, 12, pp2557-, (SCI)
2018 Hsu, T. C., P. J. Yi, T. U. Lee, and J. R. Liu*, Probiotic characteristics and zearalenone-removal ability of a Bacillus licheniformis strain, PLoS One, 13, ppe0194866-, (SCI)
2018 Limaye, A., R. C. Yu, C. C. Chou, J. R. Liu*, and K. C. Cheng*, Protective and detoxifying effects conferred by dietary selenium and curcumin against AFB1-mediated toxicity in livestock: a review, Toxins, 10, pp25-, (SCI)
2017 Yang, W. C., T. C. Hsu, K. C. Cheng*, and J. R. Liu*, Expression of the Clonostachys rosea lactonohydrolase gene by Lactobacillus reuteri to increase its zearalenone-removing ability, Microbial Cell Factories, 16, pp69-, (SCI)
2017 Lee, A., K. C. Cheng*, and J. R. Liu*, Isolation and characterization of a Bacillus amyloliquefaciens strain with zearalenone removal ability and its probiotic potential, PLoS One, 12, ppe0182220-, (SCI)
2016 Chen, W. J., T. Y. Kuo, F. C. Hsieh, P. Y. Chen, C. S. Wang, Y. L. Shih, Y. M. Lai, J. R. Liu, Y. L. Yang*, and M. C. Shih*, Involvement of type VI secretion system in secretion of iron chelator pyoverdine in Pseudomonas taiwanensis, Scientific Reports, 6, pp32950-, (SCI)
2016 Fu, G. H., J. F. Ma, L. H. Wang, X. Yang, J. R. Liu, and X. Zhao*, Effect of degradation of zearalenone-contaminated feed by Bacillus licheniformis CK1 on postweaning female piglets, Toxins, 8, pp300-, (SCI)
2015 Tseng, C. W., D. J. Yeh, F. T. Chuang, S. C. Lee, and J. R. Liu*, Immobilization of Piromyces rhizinflata β-glucanase on poly(dimethylsiloxane) and Si wafer and prediction of optimum reaction for enzyme activity, Preparative Biochemistry & Biotechnology, 45, pp42-55., (SCI)
2015 Chen, C. C., J. W. Huang, P. Zhao, T. P. Ko, C. H. Huang, H. C. Chan, Z. Huang, W. Liu, Y. S. Cheng, J. R. Liu*, and R. T. Guo*, Structural analyses and yeast production of the β-1,3-1,4-glucanase catalytic module encoded by the licB gene of Clostridium thermocellum, Enzyme and Microbial Technology, 71, pp1-7, (SCI)
2014 Tseng, C. W., C. Y. Liao, Y. Sun, C. C. Peng, J. T. C. Tzen, R. T. Guo*, and J. R. Liu*, Immobilization of Clostridium cellulolyticum D-psicose 3-epimerase on artificial oil bodies, Journal of Agricultural and Food Chemistry, 62, pp6771-6776, (SCI)
2014 Hsueh, H. Y., B. Yu, C. T. Liu and Je-Ruei Liu*, Increase of the adhesion ability and display of a rumen fungal xylanase on the cell surface of Lactobacillus casei by using a listerial cell-wall-anchoring protein, Journal of the Science of Food and Agriculture, 94, pp576-584, (SCI)
2014 Wu, T. Z., C. C. Chen, Y. S. Cheng, T. P. Ko, C. Y. Lin, H. L. Lai, T. Y. Huang, J. R. Liu*, and R. T. Guo*, Improving specific activity and thermostability of Escherichia coli phytase by structure-based rational design, Journal of Biotechnology, 175, pp1-6, (SCI)
2014 Cheng, Y. S., C. H. Huang, C. C. Chen, T. Y. Huang, T. P. Ko, J. W. Huang, T. H. Wu, J. R. Liu*, and R. T. Guo*, Structural and mutagenetic analyses of a 1,3-1,4-β-glucanase from Paecilomyces thermophila, Biochimica et Biophysica Acta-Proteins and Proteomics, 1844, pp366-373, (SCI)
2014 Huang, J. W., C. C. Chen, C. H. Huang, T. Y. Huang, T. H. Wu, Y. S. Cheng, T. P. Ko, C. Y. Lin, J. R. Liu*, and R. T. Guo*, Improving the specific activity of beta-mannanase from Aspergillus niger BK01 by structure-based rational design, Biochimica et Biophysica Acta -Proteins and Proteomics, 1844, pp663-669, (SCI)
2014 Cheng, Y. S., C. H. Huang, C. C. Chen, T. Y. Huang, T. P. Ko, J. W. Huang, T. H. Wu, J. R. Liu*, and R. T. Guo*, Crystallization and preliminary X-ray diffraction analyisi of a novel β-L-arabinofuranosidase (HypBA1) from Bifidobacterium longum, Acta Crystallographica Section F-Structural Biology and Crystallization Communications, F70, pp636-638, (SCI)
2014 Cheng, H. L., C. Y. Hu, S. H. Lin, J. Y. Wang, J. R. Liu, and Y. C. Chen*, Characterization of two truncated forms of xylanase recombinantly expressed by Lactobacillus reuteri with an introduced rumen fungal xylanase gene., Enzyme and Microbial Technology, 54-65, pp6-10, (SCI)
2014 Chen, Y. S., C. C. Chen, C. H. Huang, T. P. Ko, W. Luo, J. W. Huang, J. R. Liu, and R. T. Guo*, Structural analysis of a glycoside hydrolase family 11 xylanase from Neocallimastix patriciarum, 289, pp11020-11028, (SCI)
2014 Chen, W. J., F. C. Hsieh, J. R. Liu*, and M. C. Shih*, Characterization of an insecticidal toxin and pathogenicity of Pseudomonas taiwanensis against insects, PLoS Pathogens, Accepted, (SCI)
2013 Tseng, S. J., Y. F. Zeng, Y. F. Deng, P. C. Yang, J. R. Liu*, and I. M. Kempson*, Switchable delivery of small interfering RNA using a negatively-charged pH-responsive polyethylenimine-based polyelectrolyte complex, Chemical Communications, 49, pp 2670-2672, (SCI)
2013 Liu, J. R., Y. L. Ye, T. Y. Lin, Y. W. Wang, and C. C. Peng*, Effect of floral sources on the antioxidant, antimicrobial, and anti-inflammatory activities of honeys in Taiwan, Food Chemistry, 139 , pp 938-943, (SCI)
2013 Jiang, T., H. C. Chan, C. H. Huang, T. P. Ko, T. Y. Huang, J. R. Liu, and R. T Guo*, Substrate binding to a GH131 β-glucanase catalytic domain from Podospora anserina, Biochemical and Biophysical Research Communications, 438, pp 193-197, (SCI)
2013 Hsueh, H. Y., B. Yu, C. T. Liu and Je-Ruei Liu, Increase of the adhesion ability and display of a rumen fungal xylanase on the cell surface of Lactobacillus casei by using a listerial cell-wall-anchoring protein., Journal of the Science of Food and Agriculture, DOI 10.1002/jsfa.6298, (SCI)
2012 Zeng, Y. F., S. J. Tseng, I. M. Kempson, S. F. Peng, W. T. Wu, and J. R. Liu*, Controlled delivery of recombinant adeno-associated virus serotype 2 using pH-sensitive poly(ethylene glycol)-poly-L-histidine hydrogels, Biomaterials, 33, pp9239-9245, (SCI)
2012 Pai, C. K., H. T. Wang, R. T. Guo, and J. R. Liu*, The construction of bifunctional fusion xylanolytic enzymes and the prediction of optimum reaction conditions for the enzyme activity, BioResources, 7, pp5647-5665, (SCI)
2012 Cheng, Y. S., T. P. Ko, J. W. Huang, T. H. Wu, C. Y. Lin, W. Luo, Q, Li, Y. Ma, C. H. Huang, A. H. J. Wang, J. R. Liu*, and R. T. Guo*, Enhanced activity of Thermotoga maritima cellulase 12A by mutating a unique surface loop, Applied Microbiology and Biotechnology, 95, pp661-669, (SCI)
2012 Wang, S. Y., K. N. Chen, Y. M. Lo, M. L. Chiang, H. C. Chen, J. R. Liu and M. J. Chen*, Investigation of microorganisms involved in biosynthesis of the kefir grain, Food Microbiology, 32, pp 274-285, (SCI)
2012 Huang, J. W., Y. S. Cheng, T. P. Ko, C. Y. Lin, H. L. Lai, C. C. Chen, Y. Ma, Y, Zheng, C. H. Huang, P. Zou, J. R. Liu*, and R. T. Guo*, Rational design to improve thermostability and specific activity of the truncated Fibrobacter succinogenes 1,3-1,4-β-D-glucanase, Applied Microbiology and Biotechnology, 94, pp111-121, (SCI)
2011 Wu, T. H., C. H. Huang, T. P. Ko, H. L. Lai, Y. Ma, C. C. Chen, Y. S. Cheng, J. R. Liu*, and R. T. Guo*, Diverse substrate recognition mechanism revealed by Thermotoga maritima Cel5A structures in complex with cellotetraose, cellobiose and mannotriose, Biochimica et Biophysica Acta-Proteins and Proteomics, 1814, pp1832-1840, (SCI)
2011 Zeng, Y. F., T. P. Ko, H. L. Lai, Y. S. Cheng, T. H. Wu, Y. Ma, C. C. Chen, C. S. Yang, K. J. Cheng, C. H. Huang, R. T. Guo*, and J. R. Liu, Crystal structures of Bacillus alkaline phytase in complex with divalent metal ions and inositol hexasulfate, Journal of Molecular Biology, 409, pp214-224, (SCI)
2011 Huang, S. J., M. J. Chen, P. Y. Yueh, B. Yu, Xin Zhao, and J. R. Liu*, Display of Fibrobacter succinogenes β-glucanase on the cell surface of Lactobacillus reuteri, Journal of Agricultural and Food Chemistry, 59, pp1744-1751, (SCI)
2011 Cheng, Y. S., T. P. Ko, T. H. Wu, Y. Ma, C. H. Huang, H. L. Lai, A. H. J. Wang, J. R. Liu*, and R. T. Guo*, Crystal structure and substrate-binding mode of cellulase 12A from Thermotoga maritime, Proteins-Structure Function and Bioinformatics, 79, pp1193-1204, (SCI)
2011 Chu, C. Y., C. W. Tseng, P. Y. Yueh, C. H. Duan, and J. R. Liu*, Molecular cloning and characterization of a β-glucanase from Piromyces rhizinflatus, Journal of Bioscience and Bioengineering, 111, pp541-546, (SCI)
2011 Yi, P. J., C. K., Pai, and J. R. Liu*, Isolation and characterization of a Bacillus licheniformis strain capable of degrading zearalenone, World Journal of Microbiology and Biotechnology, 27, pp1035-1043, (SCI)
2011 Wang, S. Y., H. C. Chen, T. Y. Dai, I. N. Huang, J. R. Liu, and M. J. Chen*, Identification of lactic acid bacteria in Taiwanese ropy fermented milk and evaluation of their microbial ecology in bovine and caprine milk, Journal of Dairy Science, 94, pp623-635, (SCI)
2011 Tseng, C. W., T. P. Ko, R. T. Guo, J. W. Huang, H. C. Wang, C. H. Huang, Y. S. Cheng, A. H. J. Wang, and J. R. Liu*, Substrate binding of a GH5 endoglucanase from the ruminal fungus Piromyces rhizinflata, Acta Crystallographica Section F-Structural Biology and Crystallization Communications, F67, pp1189-1194, (SCI)
2010 Liu, J. R., Y. D. Lin, S. T. Chang, Y. F. Zheng, and S. L. Wang*, Molecular cloning and characterization of an insecticidal toxin from Pseudomonas taiwanensis, Journal of Agricultural and Food Chemistry, 58, pp12343-12349, (SCI)
2010 Hsueh, H. Y., P. Y. Yueh, B. Yu, Xin Zhao, and J. R. Liu*, Expression of Lactobacillus reuteri Pg4 collagen-ginding protein gene in Lactobacillus casei ATCC 393 increases its adhesion ability to Caco-2 cells, Journal of Agricultural and Food Chemistry, 58, pp12182-12191, (SCI)
2010 Pai, C. K., Y. F. Zeng, P. Y. Yueh, M. J. Chen, L. C. Tung, and J. R. Liu*, Prediction of optimum reaction conditions for the thermo-tolerant acetylxylan esterase from Neocallimastix patriciarum using the response surface methodology, Journal of Chemical Technology and Biotechnology, 85, pp628-633, (SCI)
2010 Pai, C. K., Z. Y. Wu, M. J. Chen, Y. F. Zeng, J. W. Chen, C. H. Duan, M. L. Li, and J. R. Liu*, Molecular cloning and characterization of a bifunctional xylanolytic enzyme from Neocallimastix patriciarum, Applied Microbiology and Biotechnology, 85, pp1451-1462, (SCI)
2010 Wang, S. L.*, B. S. Lin, T. W. Liang, C. L. Wang, P. C. Wu, and J. R. Liu, Purification and characterization of chitinase from a new species strain, Pseudomonas sp. TKU008, Journal of Microbiology and Biotechnology, 20, pp1001-1005, (SCI)
2009 Zeng, Y. F., Y. J. Hung, M. J. Chen, C. C. Peng, J. T. C. Tzen, and J. R. Liu*, Simultaneous refolding, purification, and immobilization of recombinant Fibrobacter succinogenes 1,3-1,4-β-D-glucanase on artificial oil bodies, Journal of Chemical Technology and Biotechnology, 84, pp1480-1485, (SCI)
2009 Chen, T. H., S. Y. Wang, K. N. Chen, J. R. Liu, and M. J. Chen*, Microbiological and chemical properties of kefir manufactured by entrapped, Journal of Dairy Science, 92, pp3002-3013, (SCI)
2008 Liu J. R., Y. C. Yang, L. S. Shi, and C. C. Peng*, Antioxidant properties of royal jelly associated with larval age and time of harvest, Journal of Agricultural and Food Chemistry, 56, pp11447-11452, (SCI)
2008 Liu, J. R., G. F. Chen, H. N. Shih, and P. C. Kuo*, Enhanced antioxidant bioactivity of Salvia miltiorrhiza (Danshen) products prepared using nanotechnology, Phytomedicine, 15, pp23-30, (SCI)
2008 Liu J. R.,* C. H. Duan, X. Zhao, J. T. C. Tzen, K,-J, Cheng, and C. K. Pai., Cloning of a rumen fungal xylanase gene and purification of the recombinant enzyme via artificial oil bodies, Applied Microbiology and Biotechnology, 79, pp225-233, (SCI)
2008 Hung, Y. J., C. C. Peng, J. T. C. Tzen, M. J. Chen*, and J. R. Liu*, Immobilization of Neocallimastix patriciarum xylanase on artificial oil bodies and statistical optimization of enzyme activity, Bioresource Technology, 99, pp8662-8666, (SCI)
2008 Wang, S. W., H. C. Chen, J. R. Liu, Y. C. Lin, and M. J. Chen*, Identification of yeasts and evaluation of their distribution in Taiwanese kefir and viili starters, Journal of Dairy Science, 91, pp3798-3805, (SCI)
2008 Yu, B., J. R. Liu, F. S. Hsiao, and P. W. S. Chiou*, Evaluation of Lactobacillus reuteri Pg4 strain expressing heterologous β-glucanase as a probiotic in poultry diet based on barley, Animal Feed Science and Technology, 141, pp82-91, (SCI)
2008 Yu, B., J. R. Liu, F. S. Hsiao, T. T. Lee, and P. W. S. Chiou, The probiotic and adherence properties of Lactobacillus reuteri Pg4 expressing the rumen microbial β-glucanase, Asian-Australasian Journal of Animal Science, 21, pp1324-1329, (SCI)
2007 Liu, J. R.,* B. Yu, X. Zhao, and K.-J. Cheng, Coexpression of rumen microbial β-glucanase and xylanase genes in Lactobacillus reuteri, Applied Microbiology and Biotechnology, 77, pp117-124, (SCI)
2007 Liu, J. R., S. F. Lai, and B. Yu*, Evaluation of an intestinal Lactobacillus reuteri strain expressing rumen fungal xylanase as a probiotic for broiler chickens fed on a wheat-based Diet, British Poultry Science, 48, pp507-514, (SCI)
2007 Yu, B., J. R. Liu, M. Y. Chiou, Y. R. Hsu, P. W. S. Chiou*, The effects of probiotic Lactobacillus reuteri Pg4 strain on intestinal characteristics and performance in broilers, Asian-Australasian Journal of Animal Science, 20, pp1243-1251, (SCI)
2006 Liu, J. R.,* S. Y. Wang, M. J. Chen, P. Y. Yueh, and C. W. Lin, Hypocholesterolemic effects of milk-kefir and soymilk-kefir in cholesterol-fed hamsters, British Journal of Nutrition, 95, pp939-946, (SCI)
2006 Chen, M. J.,* J. R. Liu, J. F. Sheu, C. W. Lin, and C. L. Chuang, Study on skin care properties of milk kefir whey, Asian-Australasian Journal of Animal Science, 19, pp905-908, (SCI)
2006 Liu, J. R.,* S. Y. Wang, M. J. Chen, P. Y. Yueh, and C. W. Lin, The anti-allergenic properties of milk kefir and soymilk kefir and their beneficial effects on the intestinal microflora, Journal of the Science of Food and Agriculture, 86, pp2527-2533, (SCI)
2005 Liu, J. R., B. Yu, F. H. Liu, K.-J. Cheng, and X. Zhao*, Expression of rumen microbial fibrolytic enzyme genes in probiotic Lactobacillus reuteri, Applied and Environmental Microbiology, 71, pp6769-6775, (SCI)
2005 Liu, J. R., M. J. Chen, and C. W. Lin*, Antimutagenicity and antioxidant activity of milk kefir and soymilk kefir, Journal of Agricultural and Food Chemistry, 53, pp2467-2474, (SCI)
2005 Liu, J. R., M. J. Chen, L. R. Chen, Y. Y. Lin, and C. W. Lin*, Antioxidative activities of kefir, Asian-Australasian Journal of Animal Science, 18, pp567-573, (SCI)
2005 Liu, J. R., B. Yu, S. H. Lin, K. -J. Cheng, and Y. C. Chen*, Direct cloning of a xylanase gene from the mixed genomic DNA of rumen fungi and its expression in intestinal Lactobacillus reuteri, FEMS Microbiology Letters, 251, pp233-241, (SCI)
2005 Chen, K. N., M. J. Chen,* J. R. Liu, C. W. Lin, and H. Y. Chiu, Optimization of incorporated prebiotics as coating materials for probiotic microencapsulation, Journal of Food Science, 70, pp260-266, (SCI)
2005 Chen, M. J.,* J. R. Liu, C. W. Lin, and Y. T. Yeh, Study of the microbial and chemical properties of goat milk kefir produced by inoculation with Taiwanese kefir grains, Asian- Australasian Journal of Animal Science, 18, pp711-715, (SCI)
2002 Liu, J. R., S. Y. Wang, Y. Y. Lin, and C. W. Lin*, Antitumor activity of milk-kefir and soymilk-kefir in tumor-bearing mice, Nutrition and Cancer, 44, pp182-187, (SCI)
2002 Liu, J. R., M. J. Chen, and C. W. Lin*, Characterization of polysaccharide and volatile compounds produced by kefir grains grown in soymilk, Journal of Food Science, 67, pp104-108, (SCI)
2000 Liu, J. R. and C. W. Lin*, Production of kefir from soymilk with or without added glucose, lactose, or sucrose, Journal of Food Science, 65, pp716-719, (SCI)
1999 Lin, C. W.,* H. L. Chen, and J. R. Liu, Identification and characterization of lactic acid bacteria and yeasts isolated from kefir grains in Taiwan, Australasian Journal Dairy Technology, 54, pp14-18, (SCI)
類別 年度 獎項名稱 頒獎單位
校內榮譽 2016 國立臺灣大學104學年度教學優良教師獎 臺灣大學
校外榮譽 2015 中國畜牧學會學術獎 中國畜牧學會
校外榮譽 2014 科技部吳大猷先生紀念獎 科技部
校內榮譽 2012 國立臺灣大學生物資源暨農學院100學年度教學優良教師獎 臺灣大學
校內榮譽 2011 國立臺灣大學99學年度教學優良教師獎 臺灣大學
校外榮譽 2009 行政院國家科學委員會補助科學與技術人員國外短期研究獎助 國科會
校內榮譽 2008 國立臺灣大學生物資源暨農學院年輕學者研究獎 臺灣大學